MolNFT v1 · #115090 · protein
1.45A resolution structure of SRPN18 from anopheles gambiae
5C98 · AGAP007691-pb: “1.45A resolution structure of SRPN18 from anopheles gambiae”. X-ray diffraction, 4 pockets (best druggability 0.73). MolNFT v1 #115090 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5C98
- Type
- protein
- Length
- 723 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- AGAP007691-pb
- UniProt
- A7UR55
- Pockets
- 4 · best druggability 0.73
Structure
x-ray diffraction · 2 distinct chains · 33% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | AGAP007691-pb | protein | 359 | 33% helix, 32% strand | A7UR55 |
| B | AGAP007691-pb | protein | 364 | 33% helix, 32% strand | A7UR55 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 576 | 0.73 | 0.81 | 80 | empty |
| 2 | 88 | 0.43 | 0.79 | 18 | empty |
| 3 | 100 | 0.43 | 0.78 | 16 | empty |
| 4 | 57 | 0.32 | 0.76 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 731 Ų buried · 9 hydrogen bonds · protein-protein
Compared structures
- 5C98 · 1.45A resolution structure of SRPN18 from Anopheles gambiae · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A7UR55
- Elsewhere: RCSB PDB 5C98 · PDBe 5C98 · UniProt A7UR55
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