MolNFT v1 · #115059 · protein
Structural insights into the redesign of a sucrose phosphorylase by induced loop repositioning
5C8B: “Structural insights into the redesign of a sucrose phosphorylase by induced loop repositioning”. X-ray diffraction, 1 ligand (BGC), 2 pockets (best druggability 0.75). MolNFT v1 #115059 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5C8B
- Type
- protein
- Length
- 504 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sucrose phosphorylase
- EC
- 2.4.1.7
- UniProt
- Q84HQ2
- Ligands
- BGC
- Pockets
- 2 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Sucrose phosphorylase (EC 2.4.1.7) | protein | 504 | 36% helix, 20% strand | Q84HQ2 |
Ligands and binding sites
- BGC · beta-D-glucopyranose · sugar · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 420 | 0.75 | 0.85 | 61 | BGC |
| 2 | 77 | 0.41 | 0.79 | 18 | empty |
Compared structures
- 5C8B · Structural insights into the redesign of a sucrose phosphorylase by induced loop… · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q84HQ2
- Elsewhere: RCSB PDB 5C8B · PDBe 5C8B · UniProt Q84HQ2
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