MolNFT v1 · #115052 · protein
Fragment-based drug discovery targeting inhibitor of apoptosis proteins: compound 20
5C84 · E3 ubiquitin-protein ligase xiap: “Fragment-based drug discovery targeting inhibitor of apoptosis proteins: compound 20”. X-ray diffraction, 2 ligands (4YL, ZN). MolNFT v1 #115052 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5C84
- Type
- protein
- Length
- 107 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- E3 ubiquitin-protein ligase xiap
- EC
- 6.3.2.-
- UniProt
- P98170
- Ligands
- 4YL, ZN
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | E3 ubiquitin-protein ligase xiap (EC 6.3.2.-) | protein | 107 | 46% helix, 7% strand | P98170 |
Ligands and binding sites
- 4YL · (2R,5R)-4-[2-(6-chloro-3,3-dimethyl-2,3-dihydro-1H-pyrrolo[3,2-c]pyridin-1-yl)-2-oxoethyl]-5-(methoxymethyl)-2-methylpiperazin-1-ium · ligand · chains A
- ZN · Zinc ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5C84 · Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Compound 20 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P98170
- Elsewhere: RCSB PDB 5C84 · PDBe 5C84 · UniProt P98170
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.