MolNFT v1 · #115005 · protein

Crystal structure of the apo topless related protein 2 (TPR2) N- terminal domain (1-209) from rice

5C6Q · ASPR2 protein: “Crystal structure of the apo topless related protein 2 (TPR2) N- terminal domain (1-209) from rice”. X-ray diffraction, 1 ligand (ZN), 3 pockets (best druggability 0.50). MolNFT v1 #115005 on GenesisL1: 3D structure…

PDB: 5C6Q
Type: protein
Length: 205 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: ASPR2 protein
UniProt: Q5NBT9
Ligands: ZN
Pockets: 3 · best druggability 0.50

Structure

x-ray diffraction · 1 distinct chain · 60% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	ASPR2 protein	protein	205	60% helix, 0% strand	Q5NBT9

Ligands and binding sites

ZN · Zinc ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	167	0.50	0.77	21	empty
2	64	0.42	0.80	13	empty
3	51	0.27	0.74	13	empty

Compared structures

5C6Q · Crystal structure of the apo TOPLESS related protein 2 (TPR2) N-terminal domain (1-209)… · the same entry in another collection · chain A against A, TM-score 1.00
Q5NBT9 · AlphaFold monomer V2.0 prediction for protein TPR1 (Q5NBT9) · a predicted model of the same protein · chain A against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5NBT9
Elsewhere: RCSB PDB 5C6Q · PDBe 5C6Q · UniProt Q5NBT9

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