MolNFT v1 · #114983 · protein

Crystal structure analysis of C4763, a uropathogenic E. COLI-specific protein

5C5Z · Glutamyl-tRNA amidotransferase: “Crystal structure analysis of C4763, a uropathogenic E. COLI-specific protein”. X-ray diffraction, 1 pocket (best druggability 0.57). MolNFT v1 #114983 on GenesisL1: 3D structure, binding sites and…

PDB: 5C5Z
Type: protein
Length: 254 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glutamyl-tRNA amidotransferase
UniProt: E2QI13
Pockets: 1 · best druggability 0.57

Structure

x-ray diffraction · 2 distinct chains · 20% helix, 41% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glutamyl-tRNA amidotransferase	protein	127	20% helix, 41% strand	E2QI13
B	Glutamyl-tRNA amidotransferase	protein	127	20% helix, 41% strand	E2QI13

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	99	0.57	0.85	22	empty

Interfaces

1 interface between chains.

A–B · 1096 Å² buried · 9 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 9 modified (engineered).

Compared structures

5C5Z · Crystal structure analysis of c4763, a uropathogenic E. coli-specific protein · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt E2QI13
Elsewhere: RCSB PDB 5C5Z · PDBe 5C5Z · UniProt E2QI13

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