MolNFT v1 · #114879 · protein
Molecular insights into the specificity of exfoliative toxins from staphylococcus aureus
5C2Z · Exfoliative toxin D2: “Molecular insights into the specificity of exfoliative toxins from staphylococcus aureus”. X-ray diffraction, 2 pockets (best druggability 0.69). MolNFT v1 #114879 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5C2Z
- Type
- protein
- Length
- 496 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Exfoliative toxin D2
- UniProt
- L0RUV7
- Pockets
- 2 · best druggability 0.69
Structure
x-ray diffraction · 2 distinct chains · 17% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Exfoliative toxin D2 | protein | 248 | 17% helix, 33% strand | L0RUV7 |
| B | Exfoliative toxin D2 | protein | 248 | 16% helix, 31% strand | L0RUV7 |
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 602 | 0.69 | 0.78 | 71 | empty |
| 2 | 132 | 0.54 | 0.82 | 31 | empty |
Interfaces
1 interface between chains.
- A–B · 586 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 5C2Z · Molecular insights into the specificity of exfoliative toxins from Staphylococcus aureus · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt L0RUV7
- Elsewhere: RCSB PDB 5C2Z · PDBe 5C2Z · UniProt L0RUV7
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