MolNFT v1 · #11469 · protein

Crystal structure of murine TCL1 at 2.5 resolution

1JNP · T-cell LEUKEMIA/LYMPHOMA protein 1A: “Crystal structure of murine TCL1 at 2.5 resolution”. X-ray diffraction, 1 pocket (best druggability 0.50). MolNFT v1 #11469 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1JNP
Type: protein
Length: 202 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: T-cell LEUKEMIA/LYMPHOMA protein 1A
UniProt: P56280
Pockets: 1 · best druggability 0.50

Structure

x-ray diffraction · 1 distinct chain · 0% helix, 42% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	T-cell LEUKEMIA/LYMPHOMA protein 1A	protein	101	0% helix, 42% strand	P56280

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	66	0.50	0.85	17	empty

Interfaces

1 interface between chains.

A–B · 463 Å² buried · 4 hydrogen bonds · protein-protein

Compared structures

1JNP · Crystal Structure of Murine Tcl1 at 2.5 Resolution · the same entry in another collection · chain A against A, TM-score 1.00
P56280 · AlphaFold monomer V2.0 prediction for T-cell LEUKEMIA/LYMPHOMA protein 1A (P56280) · a predicted model of the same protein · chain A against A, TM-score 0.90

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P56280
Elsewhere: RCSB PDB 1JNP · PDBe 1JNP · UniProt P56280

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