MolNFT v1 · #114677 · protein

Structure of proplasmepsin II from plasmodium falciparum, space group P43212

5BWY · Plasmepsin-2: “Structure of proplasmepsin II from plasmodium falciparum, space group P43212”. X-ray diffraction, 2 pockets (best druggability 0.67). MolNFT v1 #114677 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5BWY
Type: protein
Length: 376 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Plasmepsin-2
UniProt: W7FL77
Pockets: 2 · best druggability 0.67

Structure

x-ray diffraction · 1 distinct chain · 16% helix, 41% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Plasmepsin-2	protein	376	16% helix, 41% strand	W7FL77

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	499	0.67	0.78	40	empty
2	63	0.33	0.77	13	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

5BWY · Structure of proplasmepsin II from Plasmodium falciparum, Space Group P43212 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt W7FL77
Elsewhere: RCSB PDB 5BWY · PDBe 5BWY · UniProt W7FL77

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