MolNFT v1 · #114582 · protein

Structure of the C-terminal domain of LPG1496 from legionella pneumophila

5BU0: “Structure of the C-terminal domain of LPG1496 from legionella pneumophila”. X-ray diffraction, 3 pockets (best druggability 0.76). MolNFT v1 #114582 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5BU0
Type: protein
Length: 587 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: LPG1496
UniProt: G8UY02
Pockets: 3 · best druggability 0.76

Structure

x-ray diffraction · 2 distinct chains · 61% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	LPG1496	protein	295	61% helix, 3% strand	G8UY02
B	LPG1496	protein	292	61% helix, 2% strand	G8UY02

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1067	0.76	0.78	99	empty
2	222	0.53	0.77	30	empty
3	52	0.25	0.72	12	empty

Interfaces

1 interface between chains.

A–B · 340 Å² buried · 3 hydrogen bonds · protein-protein

Compared structures

5BU0 · Structure of the C-terminal domain of lpg1496 from Legionella pneumophila · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt G8UY02
Elsewhere: RCSB PDB 5BU0 · PDBe 5BU0 · UniProt G8UY02

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