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MolNFT v1 · #114568 · RNA

Crystal structure of auucu repeating RNA that causes spinocerebellar ataxia type 10 (SCA10)

5BTM · RNA (55-mer): “Crystal structure of auucu repeating RNA that causes spinocerebellar ataxia type 10 (SCA10)”. X-ray diffraction, 2 ligands (MG, NA), 4 pockets (best druggability 0.46). MolNFT v1 #114568 on GenesisL1: 3D structure…

PDB
5BTM
Type
RNA
Length
86 nucleotides
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
RNA (55-mer)
Ligands
MG, NA
Pockets
4 · best druggability 0.46

Structure

x-ray diffraction · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, BRNA (55-mer)rna43——

Ligands and binding sites

  • MG · Magnesium ion · metal · 3 copies · chains A, B
  • NA · Sodium ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12500.460.7318empty
22420.460.7319empty
3840.370.7712empty
4520.230.7210empty

Interfaces

1 interface between chains.

  • A–B · 472 Ų buried · 8 hydrogen bonds · nucleic-nucleic

Compared structures

  • 5BTM · Crystal structure of AUUCU repeating RNA that causes spinocerebellar ataxia type 10… · the same entry in another collection · chain A against A, TM-score 1.00

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