MolNFT v1 · #114450 · protein
Atomic-resolution structures of the APC/C subunits APC4 and the APC5 N-terminal domain
5BPT · MGC81278 protein: “Atomic-resolution structures of the APC/C subunits APC4 and the APC5 N-terminal domain”. X-ray diffraction, 10 pockets (best druggability 0.81). MolNFT v1 #114450 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5BPT
- Type
- protein
- Length
- 614 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- MGC81278 protein
- UniProt
- Q6NU36
- Pockets
- 10 · best druggability 0.81
Structure
x-ray diffraction · 1 distinct chain · 33% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | MGC81278 protein | protein | 614 | 33% helix, 29% strand | Q6NU36 |
Pockets
10 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 744 | 0.81 | 0.84 | 48 | empty |
| 2 | 233 | 0.65 | 0.83 | 30 | empty |
| 3 | 125 | 0.57 | 0.84 | 27 | empty |
| 4 | 171 | 0.53 | 0.78 | 22 | empty |
| 5 | 218 | 0.47 | 0.74 | 20 | empty |
Modifications
Observed in the structure: 15 modified (engineered).
Compared structures
- 5BPT · Atomic-resolution structures of the APC/C subunits Apc4 and the Apc5 N-terminal domain · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6NU36
- Elsewhere: RCSB PDB 5BPT · PDBe 5BPT · UniProt Q6NU36
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