MolNFT v1 · #114221 · protein
Crystal structure of PTLCIB4, a homolog of the limiting CO2-inducible protein lcib
5B5Y: “Crystal structure of PTLCIB4, a homolog of the limiting CO2-inducible protein lcib”. X-ray diffraction, 1 ligand (ZN), 5 pockets (best druggability 0.66). MolNFT v1 #114221 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 5B5Y
- Type
- protein
- Length
- 478 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- PTLCIB4
- Ligands
- ZN
- Pockets
- 5 · best druggability 0.66
Structure
x-ray diffraction · 2 distinct chains · 45% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | PTLCIB4 | protein | 237 | 46% helix, 22% strand | — |
| B | PTLCIB4 | protein | 241 | 45% helix, 21% strand | — |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 215 | 0.66 | 0.85 | 38 | empty |
| 2 | 194 | 0.54 | 0.79 | 25 | empty |
| 3 | 127 | 0.51 | 0.80 | 25 | empty |
| 4 | 63 | 0.39 | 0.80 | 21 | ZN, ACT |
| 5 | 58 | 0.26 | 0.74 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 2159 Ų buried · 41 hydrogen bonds · protein-protein
Compared structures
- 5B5Y · Crystal structure of PtLCIB4, a homolog of the limiting CO2-inducible protein LCIB · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 5B5Y · PDBe 5B5Y
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.