MolNFT v1 · #114209 · protein
Crystal structure of IZUMO1, the mammalian sperm ligand for egg juno
5B5K · Izumo sperm-egg fusion protein 1: “Crystal structure of IZUMO1, the mammalian sperm ligand for egg juno”. X-ray diffraction, 1 ligand (NAG). MolNFT v1 #114209 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5B5K
- Type
- protein
- Length
- 235 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Izumo sperm-egg fusion protein 1
- UniProt
- Q9D9J7
- Ligands
- NAG
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Izumo sperm-egg fusion protein 1 | protein | 235 | 43% helix, 31% strand | Q9D9J7 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains A
- EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Modifications
Observed in the structure: 5 disulfide, 1 glycan (disulfide, N-glycosylation).
Compared structures
- 5B5K · Crystal structure of Izumo1, the mammalian sperm ligand for egg Juno · the same entry in another collection · chain A against A, TM-score 1.00
- Q9D9J7 · AlphaFold monomer V2.0 prediction for izumo sperm-egg fusion protein 1 (Q9D9J7) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9D9J7
- Elsewhere: RCSB PDB 5B5K · PDBe 5B5K · UniProt Q9D9J7
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