MolNFT v1 · #114175 · protein

Sulfur transferase ttua in complex with iron sulfur cluster

5B4F: “Sulfur transferase ttua in complex with iron sulfur cluster”. X-ray diffraction, 3 ligands (SF4, ZN, SO4), 2 pockets (best druggability 0.75). MolNFT v1 #114175 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5B4F
Type: protein
Length: 294 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sulfur transferase ttua
UniProt: Q72LF3
Ligands: SF4, ZN, SO4
Pockets: 2 · best druggability 0.75

Structure

x-ray diffraction · 1 distinct chain · 50% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sulfur transferase ttua	protein	294	50% helix, 13% strand	Q72LF3

Ligands and binding sites

SF4 · Iron/sulfur cluster · ligand · chains A
ZN · Zinc ion · metal · 2 copies · chains A
SO4 · Sulfate ion · ion · 6 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1081	0.75	0.78	72	SO4, SF4
2	171	0.49	0.77	25	SO4

Compared structures

5B4F · Sulfur Transferase TtuA in complex with iron sulfur cluster · the same entry in another collection · chain A against A, TM-score 1.00
Q72LF3 · AlphaFold monomer V2.0 prediction for tRNA-5-METHYLURIDINE(54) 2-sulfurtransferase… · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q72LF3
Elsewhere: RCSB PDB 5B4F · PDBe 5B4F · UniProt Q72LF3

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.