MolNFT v1 · #11415 · protein
Anopheles dirus species B glutathione S-transferases 1-4
1JLW · Glutathione transferase GST1-4: “Anopheles dirus species B glutathione S-transferases 1-4”. X-ray diffraction, 4 pockets (best druggability 0.73). MolNFT v1 #11415 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1JLW
- Type
- protein
- Length
- 434 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glutathione transferase GST1-4
- EC
- 2.5.1.18
- UniProt
- Q9GN60
- Pockets
- 4 · best druggability 0.73
Structure
x-ray diffraction · 1 distinct chain · 62% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Glutathione transferase GST1-4 (EC 2.5.1.18) | protein | 217 | 62% helix, 6% strand | Q9GN60 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 682 | 0.73 | 0.79 | 43 | empty |
| 2 | 681 | 0.72 | 0.79 | 45 | empty |
| 3 | 119 | 0.37 | 0.74 | 21 | empty |
| 4 | 71 | 0.30 | 0.74 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 1605 Ų buried · 14 hydrogen bonds · protein-protein
Compared structures
- 1JLW · Anopheles dirus species B glutathione S-transferases 1-4 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9GN60
- Elsewhere: RCSB PDB 1JLW · PDBe 1JLW · UniProt Q9GN60
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.