MolNFT v1 · #114046 · protein
Polyketide cyclase oac from cannabis sativa, V59M mutant
5B0E · Olivetolic acid cyclase: “Polyketide cyclase oac from cannabis sativa, V59M mutant”. X-ray diffraction, 3 pockets (best druggability 0.46). MolNFT v1 #114046 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5B0E
- Type
- protein
- Length
- 204 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Olivetolic acid cyclase
- EC
- 4.4.1.26
- UniProt
- I6WU39
- Pockets
- 3 · best druggability 0.46
Structure
x-ray diffraction · 2 distinct chains · 30% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Olivetolic acid cyclase (EC 4.4.1.26) | protein | 100 | 41% helix, 31% strand | I6WU39 |
| B | Olivetolic acid cyclase (EC 4.4.1.26) | protein | 104 | 19% helix, 35% strand | I6WU39 |
Ligands and binding sites
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 62 | 0.46 | 0.82 | 15 | empty |
| 2 | 92 | 0.36 | 0.74 | 16 | empty |
| 3 | 58 | 0.28 | 0.74 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 1373 Ų buried · 27 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt I6WU39
- Elsewhere: RCSB PDB 5B0E · PDBe 5B0E · UniProt I6WU39
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.