MolNFT v1 · #113973 · protein

Crystal structure of ruminococcus albus 4-O-beta-D-mannosyl-D-glucose phosphorylase (RAMP1)

5AY9: “Crystal structure of ruminococcus albus 4-O-beta-D-mannosyl-D-glucose phosphorylase (RAMP1)”. X-ray diffraction, 6 pockets (best druggability 0.59). MolNFT v1 #113973 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5AY9
Type: protein
Length: 386 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 4-O-beta-D-mannosyl-D-glucose phosphorylase
EC: 2.4.1.281
UniProt: E6UIS7
Pockets: 6 · best druggability 0.59

Structure

x-ray diffraction · 1 distinct chain · 11% helix, 41% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	4-O-beta-D-mannosyl-D-glucose phosphorylase (EC 2.4.1.281)	protein	386	11% helix, 41% strand	E6UIS7

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	274	0.59	0.79	39	empty
2	204	0.56	0.79	20	empty
3	94	0.40	0.77	14	empty
4	75	0.34	0.75	13	empty
5	68	0.32	0.75	14	empty

Compared structures

5AY9 · Crystal structure of Ruminococcus albus 4-O-beta-D-mannosyl-D-glucose phosphorylase… · the same entry in another collection · chain A against A, TM-score 1.00
E6UIS7 · AlphaFold monomer V2.0 prediction for 4-O-beta-D-mannosyl-D-glucose phosphorylase (E6UIS7) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt E6UIS7
Elsewhere: RCSB PDB 5AY9 · PDBe 5AY9 · UniProt E6UIS7

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.