MolNFT v1 · #113942 · protein
The crystal structure of cofb, the minor pilin subunit of CFA/III from human enterotoxigenic escherichia COLI.
5AX6: “The crystal structure of cofb, the minor pilin subunit of CFA/III from human enterotoxigenic escherichia COLI.”. X-ray diffraction, 4 pockets (best druggability 0.47). MolNFT v1 #113942 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5AX6
- Type
- protein
- Length
- 481 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cofb
- UniProt
- Q93I73
- Pockets
- 4 · best druggability 0.47
Structure
x-ray diffraction · 1 distinct chain · 14% helix, 34% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cofb | protein | 481 | 14% helix, 34% strand | Q93I73 |
Ligands and binding sites
- ACT · Acetate ion · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 162 | 0.47 | 0.76 | 27 | empty |
| 2 | 127 | 0.40 | 0.74 | 18 | empty |
| 3 | 90 | 0.33 | 0.73 | 25 | empty |
| 4 | 50 | 0.26 | 0.74 | 14 | empty |
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
- 5AX6 · The crystal structure of CofB, the minor pilin subunit of CFA/III from human… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q93I73
- Elsewhere: RCSB PDB 5AX6 · PDBe 5AX6 · UniProt Q93I73
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