GL1X · GenesisL1 explorer

MolNFT v1 · #113703 · protein + RNA

Mechanism of EIF6 release from the nascent 60S ribosomal subunit

5ANB: “Mechanism of EIF6 release from the nascent 60S ribosomal subunit”. Electron microscopy. MolNFT v1 #113703 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
5ANB
Type
protein + RNA
Length
4,187 residues
Chains
12
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P34113, Q54XI5, P22685, Q54J50, Q54G86, Q54J69, Q54VN6, P14794, Q551M2, Q9Y3A5, Q7Z2Z2

Structure

electron microscopy · 12 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein398—P34113
B—protein188—Q54XI5
C—protein205—P22685
D—protein166—Q54J50
E—protein136—Q54G86
F—protein217—Q54J69
G—protein69—Q54VN6
H—protein52—P14794
I—protein224—Q551M2
J—protein250—Q9Y3A5
K—protein1120—Q7Z2Z2
N—rna1162——

Compared structures

  • Q551M2 · AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor 6 (Q551M2) · a predicted model of the same protein · chain I against A, TM-score 0.95
  • Q54XI5 · AlphaFold monomer V2.0 prediction for 60S ribosomal protein L9 (Q54XI5) · a predicted model of the same protein · chain B against A, TM-score 0.94
  • Q54G86 · AlphaFold monomer V2.0 prediction for 60S ribosomal protein L23 (Q54G86) · a predicted model of the same protein · chain E against A, TM-score 0.94
  • Q54J69 · AlphaFold monomer V2.0 prediction for 60S ribosomal protein L10 (Q54J69) · a predicted model of the same protein · chain F against A, TM-score 0.93
  • P34113 · AlphaFold monomer V2.0 prediction for 60S ribosomal protein L3 (P34113) · a predicted model of the same protein · chain A against A, TM-score 0.91
  • P14794 · AlphaFold monomer V2.0 prediction for ubiquitin-60S ribosomal protein L40 (P14794) · a predicted model of the same protein · chain H against A, TM-score 0.87
  • Q7Z2Z2 · AlphaFold monomer V2.0 prediction for elongation factor-like GTPase 1 (Q7Z2Z2) · a predicted model of the same protein · chain K against A, TM-score 0.74
  • P22685 · AlphaFold monomer V2.0 prediction for 60S acidic ribosomal protein P0 (P22685) · a predicted model of the same protein · chain C against A, TM-score 0.69
  • Q54J50 · AlphaFold monomer V2.0 prediction for 60S ribosomal protein L12 (Q54J50) · a predicted model of the same protein · chain D against A, TM-score 0.67
  • Q54VN6 · AlphaFold monomer V2.0 prediction for 60S ribosomal protein L24 (Q54VN6) · a predicted model of the same protein · chain G against A, TM-score 0.67
  • Q9Y3A5 · AlphaFold monomer V2.0 prediction for ribosome maturation protein sbds (Q9Y3A5) · a predicted model of the same protein · chain J against A, TM-score 0.63

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