MolNFT v1 · #113557 · protein
The pias-like coactivator ZMIZ1 is a direct and selective cofactor of NOTCH1 in T-cell development and leukemia
5AIZ · Zinc finger miz domain-containing protein 1: “The pias-like coactivator ZMIZ1 is a direct and selective cofactor of NOTCH1 in T-cell development and…”. X-ray diffraction, 1 ligand (UNX). MolNFT v1 #113557 on GenesisL1: 3D structure…
- PDB
- 5AIZ
- Type
- protein
- Length
- 110 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Zinc finger miz domain-containing protein 1
- UniProt
- Q9ULJ6
- Ligands
- UNX
Structure
x-ray diffraction · 1 distinct chain · 78% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Zinc finger miz domain-containing protein 1 | protein | 110 | 78% helix, 0% strand | Q9ULJ6 |
Ligands and binding sites
- UNX · Unknown atom or ion · ion · chains A
- EDO · 1,2-ethanediol · additive · chains A
- ACT · Acetate ion · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Modifications
Observed in the structure: 2 modified (engineered).
Compared structures
- 5AIZ · The PIAS-like coactivator Zmiz1 is a direct and selective cofactor of Notch1 in T-cell… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9ULJ6 · AlphaFold monomer V2.0 prediction for zinc finger miz domain- containing protein 1… · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9ULJ6
- Elsewhere: RCSB PDB 5AIZ · PDBe 5AIZ · UniProt Q9ULJ6
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