MolNFT v1 · #113537 · protein

Discovery and characterization of thermophilic limonene-1,2-epoxide hydrolases from hot spring metagenomic libraries. tomsk-sample-native

5AIF: “Discovery and characterization of thermophilic limonene-1,2-epoxide hydrolases from hot spring metagenomic…”. X-ray diffraction, 1 pocket (best druggability 0.75). MolNFT v1 #113537 on GenesisL1: 3D structure, binding sites and…

PDB: 5AIF
Type: protein
Length: 248 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Limonene-1,2-epoxide hydrolase
EC: 3.3.2.8
Pockets: 1 · best druggability 0.75

Structure

x-ray diffraction · 1 distinct chain · 31% helix, 45% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Limonene-1,2-epoxide hydrolase (EC 3.3.2.8)	protein	124	31% helix, 45% strand	—

Ligands and binding sites

IMD · Imidazole · additive · 4 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	81	0.75	0.96	17	IMD

Interfaces

1 interface between chains.

A–B · 990 Å² buried · 15 hydrogen bonds · protein-protein

Compared structures

5AIF · Discovery and characterization of thermophilic limonene-1,2-epoxide hydrolases from hot… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 5AIF · PDBe 5AIF

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.