MolNFT v1 · #113026 · protein

Electron cryo-microscopy of cowpea mosaic virus (cpmv) empty virus like particle (evlp)

5A33 · RNA2 polyprotein: “Electron cryo-microscopy of cowpea mosaic virus (cpmv) empty virus like particle (evlp)”. Electron microscopy, 5 pockets (best druggability 0.50). MolNFT v1 #113026 on GenesisL1: 3D structure, binding sites and…

PDB: 5A33
Type: protein
Length: 563 residues
Chains: 2
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RNA2 polyprotein
UniProt: P03599
Pockets: 5 · best druggability 0.50

Structure

electron microscopy · 2 distinct chains · 10% helix, 40% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RNA2 polyprotein	protein	196	10% helix, 42% strand	P03599
B	RNA2 polyprotein	protein	367	10% helix, 39% strand	P03599

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	102	0.50	0.82	19	empty
2	154	0.47	0.77	32	empty
3	150	0.43	0.75	25	empty
4	112	0.39	0.75	23	empty
5	69	0.34	0.76	15	empty

Interfaces

1 interface between chains.

A–B · 1779 Å² buried · 24 hydrogen bonds · protein-protein

Compared structures

5A33 · Electron cryo-microscopy of Cowpea Mosaic Virus (CPMV) empty virus like particle (eVLP) · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P03599
Elsewhere: RCSB PDB 5A33 · PDBe 5A33 · UniProt P03599

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.