MolNFT v1 · #113025 · protein
Electron cryo-microscopy of cowpea mosaic virus containing RNA-1 (cpmvb)
5A32 · RNA2 polyprotein: “Electron cryo-microscopy of cowpea mosaic virus containing RNA-1 (cpmvb)”. Electron microscopy, 5 pockets (best druggability 0.53). MolNFT v1 #113025 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5A32
- Type
- protein
- Length
- 557 residues
- Chains
- 2
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RNA2 polyprotein
- UniProt
- P03599
- Pockets
- 5 · best druggability 0.53
Structure
electron microscopy · 2 distinct chains · 9% helix, 41% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RNA2 polyprotein | protein | 189 | 7% helix, 44% strand | P03599 |
| B | RNA2 polyprotein | protein | 368 | 10% helix, 40% strand | P03599 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 91 | 0.53 | 0.84 | 20 | empty |
| 2 | 157 | 0.48 | 0.77 | 30 | empty |
| 3 | 141 | 0.43 | 0.75 | 30 | empty |
| 4 | 53 | 0.32 | 0.77 | 12 | empty |
| 5 | 51 | 0.30 | 0.76 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 1775 Ų buried · 20 hydrogen bonds · protein-protein
Compared structures
- 5A32 · Electron cryo-microscopy of Cowpea Mosaic Virus containing RNA-1 (CPMVb) · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03599
- Elsewhere: RCSB PDB 5A32 · PDBe 5A32 · UniProt P03599
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