MolNFT v1 · #113016 · protein + RNA
The molecular basis for flexibility in the flexible filamentous plant viruses
5A2T · Coat protein: “The molecular basis for flexibility in the flexible filamentous plant viruses”. Electron microscopy, 20 pockets (best druggability 0.88). MolNFT v1 #113016 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5A2T
- Type
- protein + RNA
- Length
- 5,225 residues
- Chains
- 26
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Coat protein; Bamboo mosaic virus
- UniProt
- O37178
- Pockets
- 20 · best druggability 0.88
Structure
electron microscopy · 2 distinct chains · 47% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y | Coat protein | protein | 204 | 47% helix, 1% strand | O37178 |
| Z | Bamboo mosaic virus | rna | 125 | — | — |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 703 | 0.88 | 0.93 | 95 | empty |
| 2 | 478 | 0.86 | 0.93 | 63 | empty |
| 3 | 412 | 0.85 | 0.93 | 50 | empty |
| 4 | 393 | 0.84 | 0.93 | 60 | empty |
| 5 | 332 | 0.83 | 0.93 | 42 | empty |
Interfaces
142 interfaces between chains.
- I–L · 1988 Ų buried · 19 hydrogen bonds · protein-protein
- T–W · 1987 Ų buried · 19 hydrogen bonds · protein-protein
- G–J · 1986 Ų buried · 19 hydrogen bonds · protein-protein
- F–N · 1986 Ų buried · 19 hydrogen bonds · protein-protein
- C–K · 1985 Ų buried · 19 hydrogen bonds · protein-protein
Compared structures
- 5A2T · The Molecular Basis for Flexibility in the Flexible Filamentous Plant Viruses · the same entry in another collection · chain H against H, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O37178
- Elsewhere: RCSB PDB 5A2T · PDBe 5A2T · UniProt O37178
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.