MolNFT v1 · #112868 · protein + DNA
Crystal structure of sulfolobus solfataricus O6-methylguanine methyltransferase in complex with modified DNA
4ZYD · Methylated-DNA--protein-cysteine methyltransferase: “Crystal structure of sulfolobus solfataricus O6-methylguanine methyltransferase in complex with modified DNA”. X-ray diffraction. MolNFT v1 #112868 on GenesisL1: 3D structure…
- PDB
- 4ZYD
- Type
- protein + DNA
- Length
- 175 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Methylated-DNA--protein-cysteine methyltransferase; DNA…
- EC
- 2.1.1.63
- UniProt
- Q97VW7
Structure
x-ray diffraction · 3 distinct chains · 36% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) | protein | 149 | 36% helix, 15% strand | Q97VW7 |
| B | DNA (5'-D(*GP*CP*CP*AP*TP*GP*(6OG)P*CP*TP*AP*GP*TP*A)-3') | dna | 13 | — | — |
| C | DNA (5'-D(*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*GP*C)-3') | dna | 13 | — | — |
Interfaces
1 interface between chains.
- B–C · 565 Ų buried · 50 hydrogen bonds · nucleic-nucleic
Modifications
Observed in the structure: 1 disulfide, 1 modified (disulfide, nucleotide modification).
Compared structures
- 4ZYD · Crystal structure of Sulfolobus solfataricus O6-methylguanine methyltransferase in… · the same entry in another collection · chain A against A, TM-score 1.00
- Q97VW7 · AlphaFold monomer V2.0 prediction for methylated-DNA--protein- cysteine methyltransferase… · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q97VW7
- Elsewhere: RCSB PDB 4ZYD · PDBe 4ZYD · UniProt Q97VW7
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