MolNFT v1 · #112813 · protein
Crystal structure of the bacteriophage T4 recombination mediator protein uvsy, lattice type II
4ZWR · Recombination protein uvsy: “Crystal structure of the bacteriophage T4 recombination mediator protein uvsy, lattice type II”. X-ray diffraction, 13 pockets (best druggability 0.61). MolNFT v1 #112813 on GenesisL1: 3D structure…
- PDB
- 4ZWR
- Type
- protein
- Length
- 926 residues
- Chains
- 7
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Recombination protein uvsy
- UniProt
- P04537
- Pockets
- 13 · best druggability 0.61
Structure
x-ray diffraction · 4 distinct chains · 78% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Recombination protein uvsy | protein | 136 | 77% helix, 0% strand | P04537 |
| C, E, F | Recombination protein uvsy | protein | 137 | 77% helix, 0% strand | P04537 |
| D | Recombination protein uvsy | protein | 135 | 76% helix, 0% strand | P04537 |
| G | Recombination protein uvsy | protein | 108 | 83% helix, 0% strand | P04537 |
Pockets
13 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 72 | 0.61 | 0.90 | 16 | empty |
| 2 | 66 | 0.54 | 0.87 | 18 | empty |
| 3 | 74 | 0.53 | 0.85 | 18 | empty |
| 4 | 83 | 0.52 | 0.84 | 20 | empty |
| 5 | 66 | 0.48 | 0.84 | 17 | empty |
Interfaces
7 interfaces between chains.
- C–D · 1547 Ų buried · 14 hydrogen bonds · protein-protein
- B–C · 1526 Ų buried · 14 hydrogen bonds · protein-protein
- A–B · 1518 Ų buried · 16 hydrogen bonds · protein-protein
- D–E · 1466 Ų buried · 11 hydrogen bonds · protein-protein
- E–F · 1456 Ų buried · 11 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 40 modified (engineered).
Compared structures
- 4ZWR · Crystal Structure of the Bacteriophage T4 recombination mediator protein UvsY, Lattice… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P04537
- Elsewhere: RCSB PDB 4ZWR · PDBe 4ZWR · UniProt P04537
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