MolNFT v1 · #112812 · protein

Crystal structure of the bacteriophage T4 recombination mediator protein uvsy, lattice type I

4ZWQ · Recombination protein uvsy: “Crystal structure of the bacteriophage T4 recombination mediator protein uvsy, lattice type I”. X-ray diffraction, 12 pockets (best druggability 0.61). MolNFT v1 #112812 on GenesisL1: 3D structure…

PDB: 4ZWQ
Type: protein
Length: 941 residues
Chains: 7
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Recombination protein uvsy
UniProt: P04537
Pockets: 12 · best druggability 0.61

Structure

x-ray diffraction · 4 distinct chains · 84% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Recombination protein uvsy	protein	136	83% helix, 0% strand	P04537
B, D, E	Recombination protein uvsy	protein	135	85% helix, 0% strand	P04537
C, F	Recombination protein uvsy	protein	134	82% helix, 0% strand	P04537
G	Recombination protein uvsy	protein	132	85% helix, 0% strand	P04537

Pockets

12 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	125	0.61	0.86	20	empty
2	75	0.57	0.88	20	empty
3	84	0.52	0.84	16	empty
4	104	0.51	0.82	23	empty
5	61	0.50	0.86	19	empty

Interfaces

7 interfaces between chains.

D–E · 1699 Å² buried · 12 hydrogen bonds · protein-protein
F–G · 1699 Å² buried · 20 hydrogen bonds · protein-protein
B–C · 1683 Å² buried · 16 hydrogen bonds · protein-protein
C–D · 1659 Å² buried · 14 hydrogen bonds · protein-protein
E–F · 1653 Å² buried · 15 hydrogen bonds · protein-protein

Compared structures

4ZWQ · Crystal Structure of the Bacteriophage T4 recombination mediator protein UvsY, Lattice… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P04537
Elsewhere: RCSB PDB 4ZWQ · PDBe 4ZWQ · UniProt P04537

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