MolNFT v1 · #112575 · protein

Coxsackievirus B3 polymerase - A341G mutant

4ZPC · RNA-dependent RNA polymerase: “Coxsackievirus B3 polymerase - A341G mutant”. X-ray diffraction, 1 pocket (best druggability 0.71). MolNFT v1 #112575 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4ZPC
Type: protein
Length: 462 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RNA-dependent RNA polymerase
UniProt: Q5UEA2
Pockets: 1 · best druggability 0.71

Structure

x-ray diffraction · 1 distinct chain · 43% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RNA-dependent RNA polymerase	protein	462	43% helix, 15% strand	Q5UEA2

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1097	0.71	0.75	98	empty

Compared structures

4ZPC · Coxsackievirus B3 Polymerase - A341G mutant · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5UEA2
Elsewhere: RCSB PDB 4ZPC · PDBe 4ZPC · UniProt Q5UEA2

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