MolNFT v1 · #112373 · protein
Small heat shock protein agsa from salmonella typhimurium: truncations at N- and C- termini
4ZJD · Aggregation suppressing protein: “Small heat shock protein agsa from salmonella typhimurium: truncations at N- and C- termini”. X-ray diffraction, 12 pockets (best druggability 0.71). MolNFT v1 #112373 on GenesisL1: 3D structure…
- PDB
- 4ZJD
- Type
- protein
- Length
- 558 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Aggregation suppressing protein
- UniProt
- D1MC98
- Pockets
- 12 · best druggability 0.71
Structure
x-ray diffraction · 1 distinct chain · 3% helix, 46% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F | Aggregation suppressing protein | protein | 93 | 3% helix, 46% strand | D1MC98 |
Pockets
12 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 814 | 0.71 | 0.76 | 67 | empty |
| 2 | 585 | 0.68 | 0.77 | 46 | empty |
| 3 | 737 | 0.68 | 0.75 | 65 | empty |
| 4 | 338 | 0.67 | 0.81 | 35 | empty |
| 5 | 580 | 0.66 | 0.76 | 47 | empty |
Interfaces
5 interfaces between chains.
- E–F · 1374 Ų buried · 29 hydrogen bonds · protein-protein
- A–B · 1151 Ų buried · 37 hydrogen bonds · protein-protein
- C–D · 913 Ų buried · 14 hydrogen bonds · protein-protein
- A–E · 22 Ų buried · 0 hydrogen bonds · protein-protein
- B–E · 17 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 4ZJD · Small heat shock protein AgsA from Salmonella typhimurium: Truncations at N- and C… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D1MC98
- Elsewhere: RCSB PDB 4ZJD · PDBe 4ZJD · UniProt D1MC98
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