MolNFT v1 · #112354 · protein
Crystal structure of trypsin activated alpha-2-macroglobulin from escherichia COLI.
4ZIQ · Uncharacterized lipoprotein yfhm: “Crystal structure of trypsin activated alpha-2-macroglobulin from escherichia COLI.”. X-ray diffraction, 1 ligand (CL), 20 pockets (best druggability 0.83). MolNFT v1 #112354 on GenesisL1: 3D…
- PDB
- 4ZIQ
- Type
- protein
- Length
- 1,450 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized lipoprotein yfhm
- UniProt
- P76578
- Ligands
- CL
- Pockets
- 20 · best druggability 0.83
Structure
x-ray diffraction · 1 distinct chain · 16% helix, 39% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uncharacterized lipoprotein yfhm | protein | 1450 | 16% helix, 39% strand | P76578 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
20 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 429 | 0.83 | 0.91 | 56 | empty |
| 2 | 852 | 0.80 | 0.83 | 73 | empty |
| 3 | 197 | 0.75 | 0.90 | 32 | CL |
| 4 | 507 | 0.69 | 0.79 | 84 | CL |
| 5 | 171 | 0.56 | 0.81 | 30 | empty |
Compared structures
- 4ZIQ · Crystal structure of trypsin activated alpha-2-macroglobulin from Escherichia coli. · the same entry in another collection · chain A against A, TM-score 1.00
- P76578 · AlphaFold monomer V2.0 prediction for alpha-2-macroglobulin (P76578) · a predicted model of the same protein · chain A against A, TM-score 0.70
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P76578
- Elsewhere: RCSB PDB 4ZIQ · PDBe 4ZIQ · UniProt P76578
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.