MolNFT v1 · #112324 · protein

Crystal structure of a bacterial signalling protein

4ZHV · Yfib: “Crystal structure of a bacterial signalling protein”. X-ray diffraction, 1 ligand (SO4), 4 pockets (best druggability 0.42). MolNFT v1 #112324 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4ZHV
Type: protein
Length: 273 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Yfib
UniProt: Q9I4L6
Ligands: SO4
Pockets: 4 · best druggability 0.42

Structure

x-ray diffraction · 2 distinct chains · 45% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Yfib	protein	139	45% helix, 19% strand	Q9I4L6
B	Yfib	protein	134	46% helix, 20% strand	Q9I4L6

Ligands and binding sites

SO4 · Sulfate ion · ion · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	124	0.42	0.76	19	empty
2	131	0.38	0.74	21	empty
3	84	0.37	0.76	16	empty
4	52	0.24	0.72	14	empty

Interfaces

1 interface between chains.

A–B · 566 Å² buried · 14 hydrogen bonds · protein-protein

Compared structures

4ZHV · Crystal structure of a bacterial signalling protein · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9I4L6
Elsewhere: RCSB PDB 4ZHV · PDBe 4ZHV · UniProt Q9I4L6

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