MolNFT v1 · #112058 · protein

Apo-tar from E. COLI

4Z9J · Methyl-accepting chemotaxis protein II: “Apo-tar from E. COLI”. X-ray diffraction, 4 pockets (best druggability 0.69). MolNFT v1 #112058 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4Z9J
Type: protein
Length: 316 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Methyl-accepting chemotaxis protein II
UniProt: P07017
Pockets: 4 · best druggability 0.69

Structure

x-ray diffraction · 1 distinct chain · 81% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Methyl-accepting chemotaxis protein II	protein	158	81% helix, 0% strand	P07017

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	573	0.69	0.78	50	empty
2	68	0.49	0.84	18	empty
3	120	0.45	0.78	20	empty
4	53	0.32	0.77	12	empty

Interfaces

1 interface between chains.

A–B · 1238 Å² buried · 14 hydrogen bonds · protein-protein

Compared structures

4Z9J · Apo-Tar from E. coli · the same entry in another collection · chain A against A, TM-score 1.00
P07017 · AlphaFold monomer V2.0 prediction for methyl-accepting chemotaxis protein II (P07017) · a predicted model of the same protein · chain A against A, TM-score 0.88

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P07017
Elsewhere: RCSB PDB 4Z9J · PDBe 4Z9J · UniProt P07017

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