MolNFT v1 · #111860 · protein

Structure of the ketosynthase of module 2 of C0ZGQ5 (trans-at pks) from brevibacillus brevis

4Z37 · Putative mixed polyketide SYNTHASE/NON-ribosomal peptide…: “Structure of the ketosynthase of module 2 of C0ZGQ5 (trans-at pks) from brevibacillus brevis”. X-ray diffraction, 6 pockets (best druggability 0.73). MolNFT v1 #111860 on…

PDB: 4Z37
Type: protein
Length: 607 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative mixed polyketide SYNTHASE/NON-ribosomal peptide synthetase
UniProt: C0ZGQ5
Pockets: 6 · best druggability 0.73

Structure

x-ray diffraction · 1 distinct chain · 38% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative mixed polyketide SYNTHASE/NON-ribosomal peptide synthetase	protein	607	38% helix, 20% strand	C0ZGQ5

Pockets

6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	580	0.73	0.81	55	empty
2	321	0.66	0.81	48	empty
3	219	0.61	0.81	39	empty
4	102	0.46	0.79	19	empty
5	79	0.31	0.73	17	empty

Modifications

Observed in the structure: 1 modified (oxidation).

Compared structures

4Z37 · Structure of the ketosynthase of module 2 of C0ZGQ5 (trans-AT PKS) from Brevibacillus… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt C0ZGQ5
Elsewhere: RCSB PDB 4Z37 · PDBe 4Z37 · UniProt C0ZGQ5

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