MolNFT v1 · #111841 · protein

High resolution crystal structure of short hoefavidin-hoef-peptide complex

4Z2O · Avidin family: “High resolution crystal structure of short hoefavidin-hoef-peptide complex”. X-ray diffraction, 1 pocket (best druggability 0.54). MolNFT v1 #111841 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4Z2O
Type: protein
Length: 138 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Avidin family; Hoef-peptide
UniProt: A9D857
Pockets: 1 · best druggability 0.54

Structure

x-ray diffraction · 2 distinct chains · 0% helix, 60% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Avidin family	protein	127	0% helix, 62% strand	A9D857
P	Hoef-peptide	protein	11	0% helix, 36% strand	—

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	79	0.54	0.85	16	empty

Interfaces

1 interface between chains.

A–P · 597 Å² buried · 9 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

4Z2O · High resolution crystal structure of short hoefavidin-hoef-peptide complex · the same entry in another collection · chain A against A, TM-score 1.00
A9D857 · AlphaFold monomer V2.0 prediction for hoefavidin (A9D857) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A9D857
Elsewhere: RCSB PDB 4Z2O · PDBe 4Z2O · UniProt A9D857

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.