MolNFT v1 · #111840 · protein

Crystal structure of human fact SPT16 middle domain

4Z2N · Fact complex subunit SPT16: “Crystal structure of human fact SPT16 middle domain”. X-ray diffraction, 1 pocket (best druggability 0.33). MolNFT v1 #111840 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4Z2N
Type: protein
Length: 268 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Fact complex subunit SPT16
UniProt: Q9Y5B9
Pockets: 1 · best druggability 0.33

Structure

x-ray diffraction · 1 distinct chain · 28% helix, 38% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Fact complex subunit SPT16	protein	268	28% helix, 38% strand	Q9Y5B9

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	83	0.33	0.74	18	empty

Compared structures

4Z2N · Crystal structure of human FACT SPT16 middle domain · the same entry in another collection · chain A against A, TM-score 1.00
Q9Y5B9 · AlphaFold monomer V2.0 prediction for fact complex subunit SPT16 (Q9Y5B9) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9Y5B9
Elsewhere: RCSB PDB 4Z2N · PDBe 4Z2N · UniProt Q9Y5B9

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