MolNFT v1 · #111633 · protein

Pyrococcus furiosus mcm N-terminal domain with zinc-binding subdomain B deleted

4YWK · Cell division control protein 21: “Pyrococcus furiosus mcm N-terminal domain with zinc-binding subdomain B deleted”. X-ray diffraction, 8 pockets (best druggability 0.55). MolNFT v1 #111633 on GenesisL1: 3D structure, binding sites…

PDB: 4YWK
Type: protein
Length: 377 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cell division control protein 21
UniProt: Q8U3I4
Pockets: 8 · best druggability 0.55

Structure

x-ray diffraction · 2 distinct chains · 36% helix, 33% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cell division control protein 21	protein	184	36% helix, 34% strand	Q8U3I4
B	Cell division control protein 21	protein	193	36% helix, 33% strand	Q8U3I4

Pockets

8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	223	0.55	0.78	24	empty
2	199	0.50	0.76	24	empty
3	158	0.49	0.78	22	empty
4	125	0.48	0.78	24	empty
5	54	0.39	0.81	15	empty

Interfaces

1 interface between chains.

A–B · 994 Å² buried · 6 hydrogen bonds · protein-protein

Compared structures

4YWK · Pyrococcus furiosus MCM N-terminal domain with Zinc-binding subdomain B deleted · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8U3I4
Elsewhere: RCSB PDB 4YWK · PDBe 4YWK · UniProt Q8U3I4

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