MolNFT v1 · #11163 · protein
Solution structure of the SH3 domain from C-terminal src kinase complexed with a peptide from the tyrosine phosphatase pep
1JEG · Tyrosine-protein kinase csk: “Solution structure of the SH3 domain from C-terminal src kinase complexed with a peptide from the tyrosine…”. Solution nmr. MolNFT v1 #11163 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1JEG
- Type
- protein
- Length
- 78 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tyrosine-protein kinase csk; Hematopoietic cell protein-tyrosine phosphatase 70Z-pep
- EC
- 2.7.1.112, 3.1.3.48
- UniProt
- P41241, P29352
Structure
solution nmr · 2 distinct chains · 9% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tyrosine-protein kinase csk (EC 2.7.1.112) | protein | 60 | 5% helix, 42% strand | P41241 |
| B | Hematopoietic cell protein-tyrosine phosphatase 70Z-pep (EC 3.1.3.48) | protein | 18 | 22% helix, 0% strand | P29352 |
Interfaces
1 interface between chains.
- A–B · 620 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
- 1JEG · Solution structure of the SH3 domain from C-terminal Src Kinase complexed with a peptide… · the same entry in another collection · chain A against A, TM-score 1.00
- P41241 · AlphaFold monomer V2.0 prediction for tyrosine-protein kinase csk (P41241) · a predicted model of the same protein · chain A against A, TM-score 0.88
- P29352 · AlphaFold monomer V2.0 prediction for tyrosine-protein phosphatase non-receptor type 22… · a predicted model of the same protein · chain B against A, TM-score 0.22
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P41241
- Every structure of UniProt P29352
- Elsewhere: RCSB PDB 1JEG · PDBe 1JEG · UniProt P41241 · UniProt P29352
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