MolNFT v1 · #111347 · protein

Crystal structure of an ABC transporter solute binding protein (IPR025997) from bacillus halodurans C-125 (BH2323, target efi- 511484) with bound myo-inositol

4YO7 · Sugar ABC transporter (sugar-binding protein): “Crystal structure of an ABC transporter solute binding protein (IPR025997) from bacillus halodurans C-125…”. X-ray diffraction, 4 ligands (INS, MG, NA), 1 pocket (best druggability…

PDB: 4YO7
Type: protein
Length: 287 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sugar ABC transporter (sugar-binding protein)
UniProt: Q9KAG4
Ligands: INS, MG, NA, CL
Pockets: 1 · best druggability 0.69

Structure

x-ray diffraction · 1 distinct chain · 46% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sugar ABC transporter (sugar-binding protein)	protein	287	46% helix, 20% strand	Q9KAG4

Ligands and binding sites

INS · 1,2,3,4,5,6-hexahydroxy-cyclohexane · ligand · chains A
MG · Magnesium ion · metal · 3 copies · chains A
NA · Sodium ion · metal · chains A
CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	101	0.69	0.92	31	CL, INS

Modifications

Observed in the structure: 12 modified (engineered).

Compared structures

4YO7 · Crystal Structure of an ABC transporter solute binding protein (IPR025997) from Bacillus… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9KAG4
Elsewhere: RCSB PDB 4YO7 · PDBe 4YO7 · UniProt Q9KAG4

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