MolNFT v1 · #111151 · protein
Anthranilate bound at active site of anthranilate phosphoribosyl transferase from acinetobacter (anprt; trpd)
4YI7 · Anthranilate phosphoribosyltransferase: “Anthranilate bound at active site of anthranilate phosphoribosyl transferase from acinetobacter (anprt; trpd)”. X-ray diffraction, 1 ligand (BE2), 1 pocket (best druggability 0.67). MolNFT v1…
- PDB
- 4YI7
- Type
- protein
- Length
- 331 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Anthranilate phosphoribosyltransferase
- EC
- 2.4.2.18
- UniProt
- P00500
- Ligands
- BE2
- Pockets
- 1 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 53% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Anthranilate phosphoribosyltransferase (EC 2.4.2.18) | protein | 331 | 53% helix, 13% strand | P00500 |
Ligands and binding sites
- BE2 · 2-aminobenzoic acid · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 539 | 0.67 | 0.78 | 63 | BE2 |
Compared structures
- 4YI7 · Anthranilate bound at active site of anthranilate phosphoribosyl transferase from… · the same entry in another collection · chain A against A, TM-score 1.00
- P00500 · AlphaFold monomer V2.0 prediction for anthranilate phosphoribosyltransferase (P00500) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00500
- Elsewhere: RCSB PDB 4YI7 · PDBe 4YI7 · UniProt P00500
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.