MolNFT v1 · #110925 · protein

Crystal structure of the bovine fructose transporter GLUT5 in an open inward-facing conformation

4YB9 · Solute carrier family 2, facilitated glucose transporter…: “Crystal structure of the bovine fructose transporter GLUT5 in an open inward-facing conformation”. X-ray diffraction, 3 pockets (best druggability 0.82). MolNFT v1 #110925…

PDB: 4YB9
Type: protein
Length: 437 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Solute carrier family 2, facilitated glucose transporter member 5
UniProt: P58353
Pockets: 3 · best druggability 0.82

Structure

x-ray diffraction · 1 distinct chain · 74% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
D	Solute carrier family 2, facilitated glucose transporter member 5	protein	437	74% helix, 0% strand	P58353

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1066	0.82	0.83	95	empty
2	50	0.35	0.78	16	empty
3	63	0.31	0.74	14	empty

Compared structures

4YB9 · Crystal structure of the Bovine Fructose transporter GLUT5 in an open inward-facing… · the same entry in another collection · chain D against D, TM-score 1.00
P58353 · AlphaFold monomer V2.0 prediction for solute carrier family 2, facilitated glucose… · a predicted model of the same protein · chain D against A, TM-score 0.86

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P58353
Elsewhere: RCSB PDB 4YB9 · PDBe 4YB9 · UniProt P58353

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