MolNFT v1 · #110538 · protein

Shigella flexneri effector ospi C62S mutant

4XZX · ORF169B: “Shigella flexneri effector ospi C62S mutant”. X-ray diffraction, 2 pockets (best druggability 0.38). MolNFT v1 #110538 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4XZX
Type: protein
Length: 192 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: ORF169B
UniProt: Q8VSD5
Pockets: 2 · best druggability 0.38

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	ORF169B	protein	192	41% helix, 16% strand	Q8VSD5

Ligands and binding sites

ACT · Acetate ion · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	60	0.38	0.79	18	empty
2	68	0.37	0.78	19	empty

Compared structures

4XZX · Shigella flexneri effector OspI C62S mutant · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8VSD5
Elsewhere: RCSB PDB 4XZX · PDBe 4XZX · UniProt Q8VSD5

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.