MolNFT v1 · #110493 · protein

Wild-type full length MIS16 in schizosaccharomyces japonicus

4XYH · Kinetochore protein MIS16: “Wild-type full length MIS16 in schizosaccharomyces japonicus”. X-ray diffraction, 3 pockets (best druggability 0.74). MolNFT v1 #110493 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4XYH
Type: protein
Length: 375 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Kinetochore protein MIS16
UniProt: B6K598
Pockets: 3 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 10% helix, 44% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Kinetochore protein MIS16	protein	375	10% helix, 44% strand	B6K598

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	385	0.74	0.84	38	empty
2	112	0.41	0.76	17	empty
3	58	0.34	0.77	15	empty

Compared structures

4XYH · Wild-type full length Mis16 in Schizosaccharomyces japonicus · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B6K598
Elsewhere: RCSB PDB 4XYH · PDBe 4XYH · UniProt B6K598

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