MolNFT v1 · #110432 · protein
Histidine-containing phosphocarrier protein (hpr) and antisigma factor rsd complex
4XWJ · Regulator of sigma D: “Histidine-containing phosphocarrier protein (hpr) and antisigma factor rsd complex”. X-ray diffraction, 1 pocket (best druggability 0.42). MolNFT v1 #110432 on GenesisL1: 3D structure, binding sites and…
- PDB
- 4XWJ
- Type
- protein
- Length
- 236 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Regulator of sigma D; Phosphocarrier protein hpr
- EC
- 2.7.11.-
- UniProt
- P0AFX4, P0AA04
- Pockets
- 1 · best druggability 0.42
Structure
x-ray diffraction · 2 distinct chains · 68% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Regulator of sigma D | protein | 153 | 87% helix, 0% strand | P0AFX4 |
| B | Phosphocarrier protein hpr (EC 2.7.11.-) | protein | 83 | 33% helix, 28% strand | P0AA04 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 93 | 0.42 | 0.78 | 26 | empty |
Interfaces
1 interface between chains.
- A–B · 765 Ų buried · 14 hydrogen bonds · protein-protein
Compared structures
- 4XWJ · Histidine-containing phosphocarrier protein (HPr) and antisigma factor Rsd complex · the same entry in another collection · chain A against A, TM-score 1.00
- P0AA04 · AlphaFold monomer V2.0 prediction for phosphocarrier protein hpr (P0AA04) · a predicted model of the same protein · chain B against A, TM-score 0.98
- P0AFX4 · AlphaFold monomer V2.0 prediction for regulator of sigma D (P0AFX4) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0AFX4
- Every structure of UniProt P0AA04
- Elsewhere: RCSB PDB 4XWJ · PDBe 4XWJ · UniProt P0AFX4 · UniProt P0AA04
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.