MolNFT v1 · #110382 · protein
Crystal structure of an endo-beta-1,4-xylanase (glycoside hydrolase family 10/GH10) enzyme from aspergillus niger
4XUY · Probable endo-1,4-beta-xylanase C: “Crystal structure of an endo-beta-1,4-xylanase (glycoside hydrolase family 10/GH10) enzyme from aspergillus…”. X-ray diffraction, 1 ligand (SO4), 4 pockets (best druggability 0.55). MolNFT v1…
- PDB
- 4XUY
- Type
- protein
- Length
- 604 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Probable endo-1,4-beta-xylanase C
- EC
- 3.2.1.8
- UniProt
- A2QFV7
- Ligands
- SO4
- Pockets
- 4 · best druggability 0.55
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Probable endo-1,4-beta-xylanase C (EC 3.2.1.8) | protein | 302 | 43% helix, 20% strand | A2QFV7 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 327 | 0.55 | 0.75 | 37 | GOL |
| 2 | 104 | 0.36 | 0.74 | 20 | empty |
| 3 | 57 | 0.30 | 0.75 | 13 | empty |
| 4 | 54 | 0.29 | 0.75 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 567 Ų buried · 11 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide, 2 modified (disulfide, cyclization).
Compared structures
- 4XUY · Crystal structure of an endo-beta-1,4-xylanase (glycoside hydrolase family 10/GH10)… · the same entry in another collection · chain A against A, TM-score 1.00
- A2QFV7 · AlphaFold monomer V2.0 prediction for probable endo-1,4-beta-xylanase C (A2QFV7) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A2QFV7
- Elsewhere: RCSB PDB 4XUY · PDBe 4XUY · UniProt A2QFV7
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.