MolNFT v1 · #110379 · protein
Crystal structure of a glycoside hydrolase family 105 (GH105) enzyme from thielavia terrestris
4XUV · Glycoside hydrolase family 105 protein: “Crystal structure of a glycoside hydrolase family 105 (GH105) enzyme from thielavia terrestris”. X-ray diffraction, 5 pockets (best druggability 0.64). MolNFT v1 #110379 on GenesisL1: 3D…
- PDB
- 4XUV
- Type
- protein
- Length
- 662 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glycoside hydrolase family 105 protein
- UniProt
- G2QVG2
- Pockets
- 5 · best druggability 0.64
Structure
x-ray diffraction · 2 distinct chains · 64% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glycoside hydrolase family 105 protein | protein | 332 | 64% helix, 7% strand | G2QVG2 |
| B | Glycoside hydrolase family 105 protein | protein | 330 | 65% helix, 7% strand | G2QVG2 |
Ligands and binding sites
- GOL · Glycerol · additive · 3 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 147 | 0.64 | 0.86 | 31 | empty |
| 2 | 152 | 0.56 | 0.82 | 21 | empty |
| 3 | 141 | 0.56 | 0.82 | 23 | empty |
| 4 | 153 | 0.48 | 0.77 | 25 | empty |
| 5 | 84 | 0.35 | 0.75 | 17 | GOL |
Interfaces
1 interface between chains.
- A–B · 1333 Ų buried · 8 hydrogen bonds · protein-protein
Compared structures
- 4XUV · Crystal structure of a glycoside hydrolase family 105 (GH105) enzyme from Thielavia… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G2QVG2
- Elsewhere: RCSB PDB 4XUV · PDBe 4XUV · UniProt G2QVG2
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