Structural studies of potassium transport protein ktra regulator of conductance of K+ (rck) C domain in complex with cyclic diadenosine monophosphate (C-di-AMP)

Structure

x-ray diffraction · 1 distinct chain · 27% helix, 32% strand (DSSP).

Ligands and binding sites

• 2BA · (2r,3r,3as,5r,7ar,9r,10r,10as,12r,14ar)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-D:3', 2'-J][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5, 10,12-tetrol 5,12-dioxide · ligand · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Interfaces

1 interface between chains.

• A–B · 1221 Ų buried · 11 hydrogen bonds · protein-protein

Compared structures

• 4XTT · Structural Studies of Potassium Transport Protein KtrA Regulator of Conductance of K+… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt J9USJ9
• Elsewhere: RCSB PDB 4XTT · PDBe 4XTT · UniProt J9USJ9