MolNFT v1 · #110230 · protein

The crystal structure of the oas-like domain (old) of human oasl

4XQ7 · 2'-5'-oligoadenylate synthase-like protein: “The crystal structure of the oas-like domain (old) of human oasl”. X-ray diffraction, 3 pockets (best druggability 0.75). MolNFT v1 #110230 on GenesisL1: 3D structure, binding sites and…

PDB: 4XQ7
Type: protein
Length: 334 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 2'-5'-oligoadenylate synthase-like protein
UniProt: Q15646
Pockets: 3 · best druggability 0.75

Structure

x-ray diffraction · 1 distinct chain · 49% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	2'-5'-oligoadenylate synthase-like protein	protein	334	49% helix, 15% strand	Q15646

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	608	0.75	0.81	46	empty
2	72	0.41	0.80	17	empty
3	63	0.36	0.78	17	empty

Modifications

Observed in the structure: 1 modified (artifact).

Compared structures

4XQ7 · The crystal structure of the OAS-like domain (OLD) of human OASL · the same entry in another collection · chain A against A, TM-score 1.00
Q15646 · AlphaFold monomer V2.0 prediction for 2'-5'-oligoadenylate synthase- like protein (Q15646) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q15646
Elsewhere: RCSB PDB 4XQ7 · PDBe 4XQ7 · UniProt Q15646

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