MolNFT v1 · #110217 · protein
The crystal structure of endov from E.COLI
4XPU · Endonuclease V: “The crystal structure of endov from E.COLI”. X-ray diffraction, 3 pockets (best druggability 0.77). MolNFT v1 #110217 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4XPU
- Type
- protein
- Length
- 418 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Endonuclease V
- EC
- 3.1.21.7
- UniProt
- B7MIY4
- Pockets
- 3 · best druggability 0.77
Structure
x-ray diffraction · 2 distinct chains · 28% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Endonuclease V (EC 3.1.21.7) | protein | 208 | 28% helix, 29% strand | B7MIY4 |
| B | Endonuclease V (EC 3.1.21.7) | protein | 210 | 28% helix, 28% strand | B7MIY4 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 817 | 0.77 | 0.81 | 80 | empty |
| 2 | 237 | 0.51 | 0.75 | 31 | empty |
| 3 | 111 | 0.39 | 0.75 | 23 | empty |
Interfaces
1 interface between chains.
- A–B · 591 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B7MIY4
- Elsewhere: RCSB PDB 4XPU · PDBe 4XPU · UniProt B7MIY4
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