MolNFT v1 · #110184 · protein
Structure of beta-ketoacyl-acp synthase I (fabb) from vibrio cholerae
4XOX · 3-oxoacyl-acp synthase: “Structure of beta-ketoacyl-acp synthase I (fabb) from vibrio cholerae”. X-ray diffraction, 5 pockets (best druggability 0.80). MolNFT v1 #110184 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4XOX
- Type
- protein
- Length
- 808 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 3-oxoacyl-acp synthase
- EC
- 2.3.1.41
- UniProt
- A0A071LMG6
- Pockets
- 5 · best druggability 0.80
Structure
x-ray diffraction · 1 distinct chain · 39% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | 3-oxoacyl-acp synthase (EC 2.3.1.41) | protein | 404 | 39% helix, 22% strand | A0A071LMG6 |
Pockets
5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 129 | 0.80 | 0.97 | 41 | empty |
| 2 | 163 | 0.63 | 0.85 | 31 | empty |
| 3 | 168 | 0.63 | 0.84 | 35 | empty |
| 4 | 146 | 0.50 | 0.79 | 30 | empty |
| 5 | 124 | 0.48 | 0.79 | 31 | empty |
Interfaces
1 interface between chains.
- A–B · 3084 Ų buried · 51 hydrogen bonds · protein-protein
Compared structures
- 4XOX · Structure of beta-ketoacyl-ACP synthase I (FabB) from Vibrio Cholerae · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A071LMG6
- Elsewhere: RCSB PDB 4XOX · PDBe 4XOX · UniProt A0A071LMG6
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