MolNFT v1 · #110082 · protein

Crystal structure of bjks from bradyrhizobium japonicum

4XLX · Uncharacterized protein BLR2150: “Crystal structure of bjks from bradyrhizobium japonicum”. X-ray diffraction, 11 pockets (best druggability 0.83). MolNFT v1 #110082 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4XLX
Type: protein
Length: 1,115 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Uncharacterized protein BLR2150
UniProt: Q45222
Pockets: 11 · best druggability 0.83

Structure

x-ray diffraction · 4 distinct chains · 74% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Uncharacterized protein BLR2150	protein	288	74% helix, 0% strand	Q45222
B	Uncharacterized protein BLR2150	protein	279	76% helix, 0% strand	Q45222
C	Uncharacterized protein BLR2150	protein	281	72% helix, 0% strand	Q45222
D	Uncharacterized protein BLR2150	protein	267	76% helix, 0% strand	Q45222

Pockets

11 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1049	0.83	0.84	78	empty
2	1105	0.82	0.83	90	empty
3	957	0.80	0.81	95	empty
4	437	0.76	0.85	47	empty
5	125	0.76	0.94	23	empty

Interfaces

4 interfaces between chains.

C–D · 1121 Å² buried · 15 hydrogen bonds · protein-protein
A–B · 1071 Å² buried · 15 hydrogen bonds · protein-protein
B–C · 726 Å² buried · 16 hydrogen bonds · protein-protein
B–D · 88 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

4XLX · Crystal structure of BjKS from Bradyrhizobium japonicum · the same entry in another collection · chain D against D, TM-score 1.00
Q45222 · AlphaFold monomer V2.0 prediction for uncharacterized protein BLR2150 (Q45222) · a predicted model of the same protein · chain B against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q45222
Elsewhere: RCSB PDB 4XLX · PDBe 4XLX · UniProt Q45222

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.